Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-chloro-6-fluorophenyl)-7-[2-[4-chloro-2-(trifluoromethyl)phenyl]ethynyl]-4,4-dimethyl-3H-chromeno[3,4-d]imidazole
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 PubChem ID
CID: 88921783
Canonical SMILES
CC1(C)Oc2cc(ccc2-c2nc([nH]c12)-c1c(F)cccc1Cl)C#Cc1ccc(Cl)cc1C(F)(F)F
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Compound Formula C27H16Cl2F4N2O
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2828 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7.76 nM
   TI
   LI
   LO
   TS