Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4,4-dimethyl-7-(2-phenylethynyl)-3H-chromeno[3,4-d]imidazol-2-yl]benzene-1,3-dicarbonitrile
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 PubChem ID
CID: 60148597
SID: 144076605
Canonical SMILES
CC1(C)Oc2cc(ccc2-c2[nH]c(nc12)-c1c(cccc1C#N)C#N)C#Cc1ccccc1
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Compound Formula C28H18N4O
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 984 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 24.76 nM
   TI
   LI
   LO
   TS