Brief Information of the Compound and Protein
Compound Name
7-oxa-13,18,20,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(19),2(22),3,5,14(21),15,17-heptaene
    Show/Hide
PubChem ID
CID: 137062026
Canonical SMILES
C1CCNc2ccc3ncc(-c4cccc(OCC1)c4)n3n2
    Show/Hide
Compound Formula C17H18N4O
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
EC50 = 337 nM
   TI
   LI
   LO
   TS