Brief Information of the Compound and Protein
Compound Name
2-[(2R,5R)-2-methyl-5-phenylmorpholin-4-yl]-8H-pyrimido[5,4-b][1,4]oxazin-7-one
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PubChem ID
CID: 54592087
SID: 131341890
Canonical SMILES
C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ncc2OCC(=O)Nc2n1
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Compound Formula C17H18N4O3
Compound Structure
Protein Name
Mineralocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 2
Uniprot ID
P08235
Gene Name
NR3C2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
IC50 = 266 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 113 nM