Brief Information of the Compound and Protein
Compound Name
5,8-dichloro-7-[(R)-hydroxy(oxetan-3-yl)methyl]-2-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1-one
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PubChem ID
CID: 137635406
Canonical SMILES
COc1cc(C)[nH]c(=O)c1CN1CCc2c(Cl)cc([C@H](O)C3COC3)c(Cl)c2C1=O
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Compound Formula C21H22Cl2N2O5
Compound Structure
Protein Name
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000180 Karpas-422 Homo sapiens (Human)  1
1
IC50 = 99 nM
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