Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5,8-dichloro-2-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-7-[(1S)-2-hydroxy-1-[(2R)-oxolan-2-yl]ethyl]-3,4-dihydroisoquinolin-1-one
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 PubChem ID
CID: 118580475
Canonical SMILES
Cc1cc(C)c(CN2CCc3c(Cl)cc([C@@H](CO)[C@H]4CCCO4)c(Cl)c3C2=O)c(=O)[nH]1
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Compound Formula C23H26Cl2N2O4
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000180 Karpas-422
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1024 nM
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