Brief Information of the Compound and Protein
Compound Name
5,8-dichloro-2-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-7-[(2R)-1-hydroxypropan-2-yl]-3,4-dihydroisoquinolin-1-one
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PubChem ID
CID: 118580460
Canonical SMILES
C[C@@H](CO)c1cc(Cl)c2CCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1Cl
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Compound Formula C20H22Cl2N2O3
Compound Structure
Protein Name
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000180 Karpas-422 Homo sapiens (Human)  1
1
IC50 = 1040 nM
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