Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride

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PubChem ID

CID: 53627818

SID: 15120660

Canonical SMILES	C[N+](C)(C)CCOC(N)=O.[Cl-] Show/Hide
Compound Formula	C6H15ClN2O2

Compound Structure

Protein Name

Protein Info

Muscarinic acetylcholine receptor M1

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Small molecule receptor (family A GPCR)

Monoamine receptor

Acetylcholine receptor

Uniprot ID

P11229

Gene Name

CHRM1

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000398	A-9 Cell Line Info	Mus musculus (Mouse)	7
1	EC50 = 3162.28 nM	TI LI LO TS
2	EC50 = 3811 nM	TI LI LO TS
3	EC50 = 5011.87 nM	TI LI LO TS
4	EC50 = 13000 nM	TI LI LO TS
5	EC50 = 15848.93 nM	TI LI LO TS
6	Ki = 3162.28 nM	TI LI LO TS
7	Ki = 20000 nM	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	6
1	EC50 = 5690 nM	TI LI LO TS
2	IC50 = 4090 nM	TI LI LO TS
3	IC50 = 10000 nM	TI LI LO TS
4	Ki = 170 nM	TI LI LO TS
5	Ki = 12022.64 nM	TI LI LO TS
6	Ki = 38018.94 nM	TI LI LO TS
CL000025	HEK-293T Cell Line Info	Homo sapiens (Human)	4
1	EC50 = 954.99 nM	TI LI LO TS
2	EC50 = 10715.19 nM	TI LI LO TS
3	IC50 = 457.09 nM	TI LI LO TS
4	Ki = 63000 nM	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	EC50 = 250 nM	TI LI LO TS
CL000035	NIH 3T3 Cell Line Info	Mus musculus (Mouse)	2
1	ED50 = 1210 nM	TI LI LO TS
2	ED50 = 6500 nM	TI LI LO TS

Biochemical Assays

1	EC50 = 4600 nM
2	Ki = 12000 nM