Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((2-(4-(methyl-[3H])piperidin-1-yl-4-[3H])-6-(trifluoromethyl)pyridin-3-yl)-methyl)-3-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)urea
    Show/Hide
 PubChem ID
CID: 137648895
Canonical SMILES
[3H]CC1([3H])CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2OCC(=O)N3)CC1
    Show/Hide
Compound Formula C22H24F3N5O3
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
Activity = 0.518 nM
   TI
   LI
   LO
   TS
2
Activity = 0.534 nM
   TI
   LI
   LO
   TS
3
Kd = 0.59 nM
   TI
   LI
   LO
   TS