Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(2,3-dihydroxypropyl)-3-[4-fluoro-3-(thiophene-2-carbonylamino)anilino]-11-oxo-6H-benzo[c][1]benzoxepine-9-carboxamide
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 PubChem ID
CID: 137647219
Canonical SMILES
OCC(O)CNC(=O)c1ccc2COc3cc(Nc4ccc(F)c(NC(=O)c5cccs5)c4)ccc3C(=O)c2c1
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Compound Formula C29H24FN3O6S
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 7.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 IC50 = 168.5 nM