Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine
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 PubChem ID
CID: 176155
SID: 49684193
Canonical SMILES
CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
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Compound Formula C21H16FN3OS
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase p38 subfamily
Uniprot ID
Q16539
Gene Name
MAPK14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 21.7 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM
2 IC50 = 19 nM
3 IC50 = 20 nM
4 IC50 = 25 nM
5 IC50 = 30 nM
6 IC50 = 35 nM
7 IC50 = 37 nM
8 IC50 = 38 nM
9 IC50 = 39 nM
10 IC50 = 40 nM
11 IC50 = 41 nM
12 IC50 = 44 nM
13 IC50 = 45 nM
14 IC50 = 48 nM
15 IC50 = 50 nM
16 IC50 = 55 nM
17 IC50 = 62 nM
18 IC50 = 65 nM
19 IC50 = 68 nM
20 IC50 = 70 nM
21 IC50 = 72 nM
22 IC50 = 100 nM
23 IC50 = 159 nM
24 IC50 = 273 nM
25 IC50 = 290 nM
26 IC50 = 462 nM
27 IC50 = 500 nM
28 IC50 = 723 nM
29 IC50 = 2000 nM
30 IC50 = 6000 nM
31 IC50 = 7000 nM
32 Kd = 4.1 nM
33 Kd = 12 nM
34 Kd = 17 nM
35 Ki = 18 nM
36 Ki = 57 nM