Brief Information of the Compound and Protein
Compound Name
2-[(2,2-difluoro-2-iodoacetyl)amino]-N-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide
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PubChem ID
CID: 137658006
Canonical SMILES
Fc1ccc(NC(=O)c2c(NC(=O)C(F)(F)I)sc3CCCCCc23)cc1
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Compound Formula C18H16F3IN2O2S
Compound Structure
Protein Name
Anoctamin-1
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Calcium-activated chloride channel
Uniprot ID
Q5XXA6
Gene Name
ANO1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  2
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
2
IC50 = 600 nM
   TI
   LI
   LO
   TS