Brief Information of the Compound and Protein
Compound Name
3-[(2-pyridin-3-ylquinazolin-4-yl)amino]benzonitrile
    Show/Hide
PubChem ID
CID: 9283400
Canonical SMILES
N#Cc1cccc(Nc2nc(nc3ccccc23)-c2cccnc2)c1
    Show/Hide
Compound Formula C20H13N5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
EC50 = 85 nM
   TI
   LI
   LO
   TS
2
IC50 = 108 nM
   TI
   LI
   LO
   TS