Brief Information of the Compound and Protein
Compound Name
3-N,3-N-dimethyl-1-N-(2-pyridin-3-ylquinazolin-4-yl)benzene-1,3-diamine
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PubChem ID
CID: 129904103
Canonical SMILES
CN(C)c1cccc(Nc2nc(nc3ccccc23)-c2cccnc2)c1
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Compound Formula C21H19N5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 1200 nM
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