Brief Information of the Compound and Protein
Compound Name
3-(2-Pyridin-3-yl-quinazolin-4-ylamino)-benzoic acid methyl ester
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PubChem ID
CID: 1186125
Canonical SMILES
COC(=O)c1cccc(Nc2nc(nc3ccccc23)-c2cccnc2)c1
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Compound Formula C21H16N4O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 362 nM
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