Brief Information of the Compound and Protein
Compound Name
N-(4-nitrophenyl)-2-pyridin-3-ylquinazolin-4-amine
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PubChem ID
CID: 137651369
Canonical SMILES
[O-][N+](=O)c1ccc(Nc2nc(nc3ccccc23)-c2cccnc2)cc1
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Compound Formula C19H13N5O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  3
1
EC50 = 12.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 21.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 64.1 nM
   TI
   LI
   LO
   TS