Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10245267, Example 138
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 PubChem ID
CID: 90442604
Canonical SMILES
Cc1ncc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1
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Compound Formula C24H23F3N4O3
Compound Structure
Protein Name
 Protein Info 
RAF proto-oncogene serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P04049
Gene Name
RAF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 460 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.652 nM