Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3-methylphenyl)-3-[4-[3-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridin-4-yl]phenyl]urea
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 PubChem ID
CID: 137657952
Canonical SMILES
Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(c23)C(F)(F)F)c1
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Compound Formula C21H16F3N5O
Compound Structure
Protein Name
 Protein Info 
Platelet-derived growth factor receptor alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P16234
Gene Name
PDGFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
GI50 = 465.2 nM
   TI
   LI
   LO
   TS
2
GI50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 5000 nM