Brief Information of the Compound and Protein
Compound Name
1-(2-fluoro-5-methylphenyl)-3-[4-(3-methyl-6-oxo-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-4-yl)phenyl]urea
    Show/Hide
PubChem ID
CID: 136269138
Canonical SMILES
Cc1n[nH]c2N=C(O)CC(c12)c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1
    Show/Hide
Compound Formula C21H20FN5O2
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS