Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-fluoro-5-methylphenyl)-3-[4-(3-methyl-6-oxo-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-4-yl)phenyl]urea
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 PubChem ID
CID: 136269138
Canonical SMILES
Cc1n[nH]c2N=C(O)CC(c12)c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1
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Compound Formula C21H20FN5O2
Compound Structure
Protein Name
 Protein Info 
Platelet-derived growth factor receptor alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P16234
Gene Name
PDGFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
GI50 = 4254 nM
   TI
   LI
   LO
   TS
2
GI50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 50000 nM