Brief Information of the Compound and Protein
Compound Name
2-[7-[[2-(2-fluoro-5-methylphenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]acetamide
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PubChem ID
CID: 137649478
Canonical SMILES
Cc1ccc(F)c(c1)-c1cc(Nc2ccnc3cn(CC(N)=O)nc23)c(C)cn1
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Compound Formula C21H19FN6O
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
>
TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6 Homo sapiens (Human)  1
1
EC50 = 251.19 nM
   TI
   LI
   LO
   TS