Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[7-[[2-(2,5-difluorophenyl)-5-methylpyridin-4-yl]amino]pyrazolo[4,3-b]pyridin-2-yl]propan-2-ol
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 PubChem ID
CID: 67469574
Canonical SMILES
CC(O)Cn1cc2nccc(Nc3cc(ncc3C)-c3cc(F)ccc3F)c2n1
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Compound Formula C21H19F2N5O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 158.49 nM
   TI
   LI
   LO
   TS
CL000907 CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 125.89 nM
   TI
   LI
   LO
   TS