Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-methoxy-N-[5-methyl-2-(6-methylpyridin-2-yl)pyridin-4-yl]quinolin-4-amine
    Show/Hide
 PubChem ID
CID: 137640764
Canonical SMILES
COc1cccc2nccc(Nc3cc(ncc3C)-c3cccc(C)n3)c12
    Show/Hide
Compound Formula C22H20N4O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 199.53 nM
   TI
   LI
   LO
   TS
CL000907 CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 31.62 nM
   TI
   LI
   LO
   TS