Brief Information of the Compound and Protein
Compound Name
N-[2-(3-fluoro-6-methylpyridin-2-yl)-5-methylpyridin-4-yl]-5-methoxyquinolin-4-amine
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PubChem ID
CID: 137655916
Canonical SMILES
COc1cccc2nccc(Nc3cc(ncc3C)-c3nc(C)ccc3F)c12
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Compound Formula C22H19FN4O
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6 Homo sapiens (Human)  1
1
EC50 = 31.62 nM
   TI
   LI
   LO
   TS