Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
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 PubChem ID
CID: 9818479
SID: 14797551
Canonical SMILES
CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23
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Compound Formula C11H13N3O
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000153 CHOP
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 669 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 186 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 546 nM
   TI
   LI
   LO
   TS
2
Ki = 573 nM
   TI
   LI
   LO
   TS
3
Ki = 6330 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2333 nM