Brief Information of the Compound and Protein
| Compound Name |
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
5-hydroxytryptamine receptor 2A
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Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
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| Uniprot ID | Gene Name | HTR2A |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 2790 nM | ||
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| 2 | Ki = 0.8 nM | ||
| 3 | Ki = 4 nM | ||
| 4 | Ki = 8.7 nM | ||
| 5 | Ki = 9 nM | ||
| 6 | Ki = 9.6 nM | ||
| 7 | Ki = 10 nM | ||
| 8 | Ki = 12.1 nM | ||
| 9 | Ki = 40 nM | ||