Brief Information of the Compound and Protein
Compound Name
3-(2-((3R,4R)-3,4-difluoropyrrolidin-1-yl)pyridin-4-yl)-5-isopropoxy-1H-indazole
    Show/Hide
PubChem ID
CID: 137658381
Canonical SMILES
CC(C)Oc1ccc2[nH]nc(-c3ccnc(N4C[C@@H](F)[C@H](F)C4)c3)c2c1
    Show/Hide
Compound Formula C19H20F2N4O
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
IC50 = 341 nM
   TI
   LI
   LO
   TS