Brief Information of the Compound and Protein
Compound Name
4-(methylamino)-2-[4-methyl-3-(propanoylamino)anilino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrimidine-5-carboxamide
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PubChem ID
CID: 122633897
Canonical SMILES
CCC(=O)Nc1cc(Nc2ncc(C(=O)Nc3cc(NC(=O)c4cccc(c4)C(F)(F)F)ccc3C)c(NC)n2)ccc1C
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Compound Formula C31H30F3N7O3
Compound Structure
Protein Name
Tyrosine-protein kinase JAK3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P52333
Gene Name
JAK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 8300 nM
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