Brief Information of the Compound and Protein
Compound Name
N-propyl-4-[[4-(2,2,2-trifluoroethylamino)furo[3,2-d]pyrimidin-2-yl]amino]benzamide
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PubChem ID
CID: 67129951
Canonical SMILES
CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3occc3n2)cc1
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Compound Formula C18H18F3N5O2
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 346 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 561 nM