Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5,5-dimethyl-8-[[4-(2-methylpropylamino)furo[3,2-d]pyrimidin-2-yl]amino]-1H-4,1-benzoxazepin-2-one
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 PubChem ID
CID: 137645333
Canonical SMILES
CC(C)CNc1nc(Nc2ccc3c(NC(=O)COC3(C)C)c2)nc2ccoc12
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Compound Formula C21H25N5O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 43 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 64 nM