Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl N-[(3R)-8-[[4-(cyclopropylamino)furo[3,2-d]pyrimidin-2-yl]amino]-5,5-dimethyl-2-oxo-3,4-dihydro-1H-1-benzazepin-3-yl]carbamate
    Show/Hide
 PubChem ID
CID: 137638523
Canonical SMILES
COC(=O)N[C@@H]1CC(C)(C)c2ccc(Nc3nc(NC4CC4)c4occc4n3)cc2NC1=O
    Show/Hide
Compound Formula C23H26N6O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 39 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM