Brief Information of the Compound and Protein
Compound Name
7-[[4-(2,2,2-trifluoroethylamino)furo[3,2-d]pyrimidin-2-yl]amino]-3,4-dihydro-1H-quinolin-2-one
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PubChem ID
CID: 137644670
Canonical SMILES
FC(F)(F)CNc1nc(Nc2ccc3CCC(=O)Nc3c2)nc2ccoc12
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Compound Formula C17H14F3N5O2
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 101 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 63 nM