Brief Information of the Compound and Protein
Compound Name
4-N-cyclopropyl-2-N-(3-methyl-2H-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine
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PubChem ID
CID: 67130050
Canonical SMILES
Cc1n[nH]c2cc(Nc3nc(NC4CC4)c4occc4n3)ccc12
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Compound Formula C17H16N6O
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 23 nM
2 IC50 = 24 nM