Brief Information of the Compound and Protein
Compound Name
2-(5-ethylsulfonylpyrazin-2-yl)-8-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-2,8-diazaspiro[4.5]decan-3-one
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PubChem ID
CID: 117852213
Canonical SMILES
CCS(=O)(=O)c1cnc(cn1)N1CC2(CC1=O)CCN(C[C@H](O)c1ccc3C(=O)OCc3c1C)CC2
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Compound Formula C25H30N4O6S
Compound Structure
Protein Name
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 127 nM
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