Brief Information of the Compound and Protein
Compound Name
1-[[5,6-dimethyl-2-(1,3-thiazol-2-yl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-methylpyrrole-2,5-dione
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PubChem ID
CID: 137658530
Canonical SMILES
CC1=CC(=O)N(Nc2nc(nc3sc(C)c(C)c23)-c2nccs2)C1=O
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Compound Formula C16H13N5O2S2
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 16.03 nM
   TI
   LI
   LO
   TS
2
IC50 = 21.44 nM
   TI
   LI
   LO
   TS