Brief Information of the Compound and Protein
Compound Name
(2Z)-2-[(6-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methylidene]-6-hydroxy-7-(piperazin-1-ylmethyl)-1-benzofuran-3-one
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PubChem ID
CID: 86681995
Canonical SMILES
Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12
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Compound Formula C21H19ClN4O3
Compound Structure
Protein Name
Serine/threonine-protein kinase pim-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase PIM family
Uniprot ID
P11309
Gene Name
PIM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.4 nM