Brief Information of the Compound and Protein
Compound Name
4-[[(6R)-7-cyano-6-ethyl-5-propan-2-yl-6H-imidazo[1,5-f]pteridin-3-yl]amino]-N-[4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-2-fluoro-5-methoxybenzamide
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PubChem ID
SID: 87796214
Canonical SMILES
CC[C@H]1N(C(C)C)c2nc(Nc3cc(F)c(cc3OC)C(=O)N[C@H]3CC[C@@H](CC3)N3CCN(CC4CC4)CC3)ncc2-n2cnc(C#N)c12
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Compound Formula C36H47FN10O2
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 3.9 nM
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