Brief Information of the Compound and Protein
Compound Name
4-[[[5-chloro-2-(4-fluorophenoxy)pyridine-3-carbonyl]amino]methyl]benzoic acid
    Show/Hide
PubChem ID
CID: 58905349
Canonical SMILES
OC(=O)c1ccc(CNC(=O)c2cc(Cl)cnc2Oc2ccc(F)cc2)cc1
    Show/Hide
Compound Formula C20H14ClFN2O4
Compound Structure
Protein Name
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 37.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 254 nM
   TI
   LI
   LO
   TS