Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(2-chloro-4-fluorophenyl)-3-methyl-1-(7H-purin-6-yl)-5,7-dihydro-4H-pyrazolo[3,4-b]pyridin-6-one
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 PubChem ID
CID: 135634901
Canonical SMILES
Cc1nn(c2NC(=O)CC(c12)c1ccc(F)cc1Cl)-c1ncnc2nc[nH]c12
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Compound Formula C18H13ClFN7O
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 39
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
O43194
Gene Name
GPR39
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
2
EC50 = 280 nM
   TI
   LI
   LO
   TS