Brief Information of the Compound and Protein
Compound Name
(3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE
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PubChem ID
CID: 895402
Canonical SMILES
Clc1ccc(cc1Cl)C(=S)N1CCOCC1
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Compound Formula C11H11Cl2NOS
Compound Structure
Protein Name
D-3-phosphoglycerate dehydrogenase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
O43175
Gene Name
PHGDH
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  2
1
IC50 = 7000 nM
   TI
   LI
   LO
   TS
2
IC50 = 24300 nM
   TI
   LI
   LO
   TS
CL000588 SiHa Homo sapiens (Human)  2
1
IC50 = 5600 nM
   TI
   LI
   LO
   TS
2
IC50 = 19100 nM
   TI
   LI
   LO
   TS