Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9434725, 186
    Show/Hide
 PubChem ID
CID: 77050662
Canonical SMILES
COc1ccc(nc1N1CCC[C@H](N)C1)-n1ncc2cnc(cc12)-c1cncc(C)n1
    Show/Hide
Compound Formula C22H24N8O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase pim-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase PIM family
Uniprot ID
P11309
Gene Name
PIM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.018 nM