Brief Information of the Compound and Protein
Compound Name
(1S)-16,18-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaene
    Show/Hide
PubChem ID
CID: 70692653
SID: 163442740
Canonical SMILES
COc1cc2C[C@@H]3N(CCc4cc5OCOc5cc34)Cc2c(OC)c1
    Show/Hide
Compound Formula C20H21NO4
Compound Structure
Protein Name
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 64.12 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 141.58 nM
   TI
   LI
   LO
   TS
2
Ki = 74.5 nM
   TI
   LI
   LO
   TS
3
Ki = 74.51 nM
   TI
   LI
   LO
   TS