Brief Information of the Compound and Protein
Compound Name
US9353093, 26
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PubChem ID
CID: 121254616
Canonical SMILES
Cc1cccc(NC(=O)Nc2csc(c2)-c2cc3ccccc3n2C(N)=O)c1
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Compound Formula C21H18N4O2S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 508 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 67 nM