Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9353093, 2
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 PubChem ID
CID: 121254611
Canonical SMILES
COC(=O)c1ccc2cc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)n(C(N)=O)c2c1
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Compound Formula C25H22N4O4
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM