Brief Information of the Compound and Protein
Compound Name
US9340555, 17
    Show/Hide
PubChem ID
CID: 117695640
Canonical SMILES
COC(=O)[C@@H]1C[C@@H](O)CN1CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1
    Show/Hide
Compound Formula C31H32FN5O6S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P17948
Gene Name
FLT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM