Brief Information of the Compound and Protein
Compound Name
US9340555, 86
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PubChem ID
CID: 86290418
Canonical SMILES
CCN(CC)C(=O)c1cc2nccc(Oc3cccc(c3)C(=O)Nc3cc(C)ccc3F)c2s1
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Compound Formula C26H24FN3O3S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM