Brief Information of the Compound and Protein
Compound Name
US9340555, 57
    Show/Hide
PubChem ID
CID: 86290273
Canonical SMILES
CCOC(=O)CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1
    Show/Hide
Compound Formula C28H26F2N4O5S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM