Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9266869, 8
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 PubChem ID
CID: 118130083
Canonical SMILES
Cc1ccc(F)c(NC(=O)Nc2cccc(c2)C#Cc2cncc(c2)C(=O)N=S(C)(C)=O)c1
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Compound Formula C24H21FN4O3S
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM