Brief Information of the Compound and Protein
Compound Name
US9233968, 27
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PubChem ID
CID: 118638432
Canonical SMILES
O=C(Nc1cccc(c1)C#Cc1ccc2nccn2n1)c1ccccc1
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Compound Formula C21H14N4O
Compound Structure
Protein Name
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 17766 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 27 nM