Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9233968, 4
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 PubChem ID
CID: 118638411
Canonical SMILES
Nc1cn2nc(ccc2n1)C#Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1
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Compound Formula C22H14F4N6O
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 423 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 73 nM